Marine Skeletons: Towards Hard Tissue Repair and Regeneration

Mar Drugs. 2018 Jul 2;16(7):225. doi: 10.3390/md16070225.

Abstract

Musculoskeletal disorders in the elderly have significantly increased due to the increase in an ageing population. The treatment of these diseases necessitates surgical procedures, including total joint replacements such as hip and knee joints. Over the years a number of treatment options have been specifically established which are either permanent or use temporary natural materials such as marine skeletons that possess unique architectural structure and chemical composition for the repair and regeneration of bone tissue. This review paper will give an overview of presently used materials and marine structures for hard tissue repair and regeneration, drugs of marine origin and other marine products which show potential for musculoskeletal treatment.

Keywords: bone repair; corals; cuttlebone; marine skeletons; musculoskeletal; seas urchin; seashells; tissue regeneration.

Publication types

  • Review

MeSH terms

  • Animal Shells*
  • Animals
  • Aquatic Organisms*
  • Biocompatible Materials / therapeutic use
  • Bone Regeneration*
  • Humans
  • Musculoskeletal Diseases / surgery*
  • Tissue Engineering
  • Tissue Scaffolds*

Substances

  • Biocompatible Materials