Rho(D) immune globulin is an immune globulin rich in IgG antibodies against erythrocyte antigen Rho(D). IgG is a normal component of breastmilk. IgG is a normal component of breastmilk that is likely to be partially destroyed in the infant's gastrointestinal tract and poorly absorbed by the infant during breastfeeding. Rho(D) immune globulin is frequently used in nursing mothers and no adverse effects have been reported in breastfed infants. No special precautions are required during breastfeeding.