Localized and targeted delivery of NSAIDs for treatment of inflammation: A review

Exp Biol Med (Maywood). 2019 Apr;244(6):433-444. doi: 10.1177/1535370218787770. Epub 2018 Jul 12.

Abstract

This work provides an overview of research currently being done exploring potential drug delivery device strategies for NSAIDs as an alternative to systemic delivery. Commentary on this field is made in an attempt to aid future experimental design, enabling researchers to determine the drugs and delivery vehicles which are most advantageous for them to pursue, as well as suggestions to standardize the reporting of such future research.

Keywords: Biomedical; drug delivery; inflammation; local delivery; non-steroidal anti-inflammatory drugs; targeted delivery.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use*
  • Bandages
  • Drug Administration Routes
  • Drug Carriers / chemistry
  • Drug Delivery Systems*
  • Humans
  • Inflammation / drug therapy*

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • Drug Carriers