Risk factors and consequences of conversion to open surgery in laparoscopic common bile duct exploration

Surg Endosc. 2018 Dec;32(12):4990-4998. doi: 10.1007/s00464-018-6263-4. Epub 2018 Jul 9.

Abstract

Background: Although laparoscopic common bile duct exploration (LCBDE) has shown many obvious advantages compared with open surgery in the treatment of common bile duct (CBD) stones, it remains unclear regarding risk factors of conversion from LCBDE to open surgery and whether conversion will counteract the advantages of LCBDE. The purpose of this study was to explore risk factors and consequences of conversion from LCBDE to open surgery.

Methods: A retrospective study was conducted, using a database of 644 patients with LCBDE between 2011 and 2017. Risk factors for conversion to open surgery were determined based on univariable and multivariable analysis. The consequences of conversion to open surgery in LCBDE were analyzed.

Results: Conversion was required in 27 (4.2%) of 644 patients undergoing LCBDE. Independent risk factors for conversion were as follows: the max diameter of stones in CBD (odds ratio (OR) 2.234, 95%CI 1.031-4.842; p = 0.042), edema of CBD (OR 12.530, 95%CI 4.633-33.887; p < 0.001), and multiple stones in CBD (OR 3.438, 95%CI: 1.133-10.428; p = 0.029). These risk factors and their combined were good predictors for conversion in LCBDE. More blood loss, longer operative time, longer postoperative hospital stay, and higher incision infection were identified in patients with conversion than those without conversion. However, no significant differences were observed regarding mortality, readmission within 30 days, reoperation, bile leakage, and intra-abdominal fluid collection.

Conclusion: Conversion to open surgery in LCBDE was associated with acute edematous CBD with large and multiple stones. Conversion can offset the advantages of LCBDE.

Keywords: Choledocholithiasis; Conversion; Laparoscopic common bile duct exploration; Primary closure.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Biliary Tract Surgical Procedures* / adverse effects
  • Biliary Tract Surgical Procedures* / methods
  • Choledocholithiasis* / diagnosis
  • Choledocholithiasis* / surgery
  • Common Bile Duct / surgery*
  • Conversion to Open Surgery* / methods
  • Conversion to Open Surgery* / statistics & numerical data
  • Female
  • Humans
  • Laparoscopy* / adverse effects
  • Laparoscopy* / methods
  • Male
  • Middle Aged
  • Outcome and Process Assessment, Health Care
  • Postoperative Complications / epidemiology
  • Retrospective Studies
  • Risk Factors
  • Severity of Illness Index