Role of Renin-Angiotensin-Aldosterone System Activation in Promoting Cardiovascular Fibrosis and Stiffness

Hypertension. 2018 Sep;72(3):537-548. doi: 10.1161/HYPERTENSIONAHA.118.11065.

Authors

Guanghong Jia^{1

2}, Annayya R Aroor^{1

2}, Michael A Hill^{3

4}, James R Sowers^{1

3

4

2}

Affiliations

¹ From the Diabetes and Cardiovascular Research Center (G.J., A.R.A., J.R.S.).
² Research Service, Truman Memorial Veterans Hospital, Columbia, MO (G.H., A.R.A., J.R.S.).
³ Department of Medical Pharmacology and Physiology (M.A.H., J.R.S.), University of Missouri School of Medicine, Columbia.
⁴ Dalton Cardiovascular Research Center, University of Missouri, Columbia (M.A.H., J.R.S.).

No abstract available

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Review

MeSH terms

Aldosterone / physiology*
Cardiovascular Diseases / physiopathology
Cardiovascular System / pathology
Cardiovascular System / physiopathology*
Fibrosis
Humans
Hypertension / physiopathology
Models, Cardiovascular
Renin-Angiotensin System / physiology*
Risk Factors
Vascular Stiffness / physiology*

Substances

Aldosterone

Grants and funding