Current review of sebaceous cell carcinoma

Curr Opin Ophthalmol. 2018 Sep;29(5):445-450. doi: 10.1097/ICU.0000000000000505.

Abstract

Purpose of review: Periocular sebaceous cell carcinoma is a rare malignancy that is often misdiagnosed leading to increased morbidity and mortality. This review aims to describe current knowledge on the disease to aid clinicians in timely diagnosis and treatment.

Recent findings: New research has shown that the diagnosis of sebaceous cell carcinoma can be aided with immunohistochemical stains. A revision in the American Joint Committee on Cancer staging system incorporates new tumor size classifications in the staging of eyelid carcinomas. Wide local excision and Mohs micrographic surgery continue to represent the standard of care for initial treatment of localized disease.

Summary: The current review highlights diagnostic and treatment modalities to allow clinicians to make timely diagnosis and tailor treatment plans for individual patient presentations.

Publication types

  • Review

MeSH terms

  • Adenocarcinoma, Sebaceous* / diagnosis
  • Adenocarcinoma, Sebaceous* / epidemiology
  • Adenocarcinoma, Sebaceous* / surgery
  • Diagnostic Errors*
  • Diagnostic Techniques, Ophthalmological*
  • Eyelid Neoplasms* / diagnosis
  • Eyelid Neoplasms* / epidemiology
  • Eyelid Neoplasms* / surgery
  • Global Health
  • Humans
  • Mohs Surgery
  • Morbidity / trends
  • Sebaceous Gland Neoplasms* / diagnosis
  • Sebaceous Gland Neoplasms* / epidemiology
  • Sebaceous Gland Neoplasms* / surgery
  • Skin Neoplasms / diagnosis*
  • Survival Rate / trends