TEMPO-Functionalized Nanoporous Au Nanocomposite for the Electrochemical Detection of H2O2

Dongxiao Wen; Qianrui Liu; Ying Cui; Huaixia Yang; Jinming Kong

doi:10.1155/2018/1710438

TEMPO-Functionalized Nanoporous Au Nanocomposite for the Electrochemical Detection of H₂O₂

Int J Anal Chem. 2018 Jun 10:2018:1710438. doi: 10.1155/2018/1710438. eCollection 2018.

Authors

Dongxiao Wen¹, Qianrui Liu², Ying Cui¹, Huaixia Yang¹, Jinming Kong²

Affiliations

¹ Pharmacy College, Henan University of Chinese Medicine, Zhengzhou 450008, China.
² School of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing 210094, China.

Abstract

A novel nanocomposite of nanoporous gold nanoparticles (np-AuNPs) functionalized with 2,2,6,6-tetramethyl-1-piperidinyloxy radical (TEMPO) was prepared; assembled carboxyl groups on gold nanoporous nanoparticles surface were combined with TEMPO by the "bridge" of carboxylate-zirconium-carboxylate chemistry. SEM images and UV-Vis spectroscopies of np-AuNPs indicated that a safe, sustainable, and simplified one-step dealloying synthesis approach is successful. The TEMPO-np-AuNPs exhibited a good performance for the electrochemical detection of H₂O₂ due to its higher number of electrochemical activity sites and surface area of 7.49 m²g^-1 for load bigger amount of TEMPO radicals. The TEMPO-functionalized np-AuNPs have a broad pH range and shorter response time for H₂O₂ catalysis verified by the response of amperometric signal under different pH and time interval. A wide linear range with a detection limit of 7.8 × 10^-7 M and a higher sensitivity of 110.403 μA mM^-1cm^-2 were obtained for detecting H₂O₂ at optimal conditions.