N-Formylation of Amines with CO2 and H2 by Using NHC-Iridium Coordination Assemblies as Solid Molecular Catalysts

Yang Zhang; Jiaquan Wang; Haibo Zhu; Tao Tu

doi:10.1002/asia.201800953

N-Formylation of Amines with CO₂ and H₂ by Using NHC-Iridium Coordination Assemblies as Solid Molecular Catalysts

Chem Asian J. 2018 Oct 18;13(20):3018-3021. doi: 10.1002/asia.201800953. Epub 2018 Aug 7.

Authors

Yang Zhang¹, Jiaquan Wang¹, Haibo Zhu¹, Tao Tu^{1

2}

Affiliations

¹ Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Department of Chemistry, Fudan University, 2205 Songhu Road, Shanghai, 200438, China.
² State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, 200032, China.

PMID: 29971931
DOI: 10.1002/asia.201800953

Abstract

One of the NHC-iridium coordination assemblies containing 1,5-cyclooctadiene (COD) and iodide ion has been demonstrated as robust, efficient, recyclable solid molecular catalyst for N-formylation of diverse primary and secondary amines with CO₂ and H₂ under mild reaction conditions. Remarkably, in the case of N,N-dimethylformamide production, even at 0.1 mol % catalyst loading under solvent-free conditions, the solid catalyst can be readily recovered by simply filtration and reused more than 10 runs without noticeable loss of activity.

Keywords: N-formylation; carbon dioxide transformation; coordination assembly; hydrogenation; iridium.

Abstract

Grants and funding