Contribution of Computed Tomographic Angiography to Pretreatment Planning of Radio-embolization of Liver Tumors

Anticancer Res. 2018 Jul;38(7):3825-3829. doi: 10.21873/anticanres.12666.

Abstract

Transarterial radio-embolization (TARE) using yttrium-90 microspheres is a promising method based on the brachytherapeutic effect of radionuclide with beta-minus decay dissolved in solid microparticles applied directly to tumor-supplying arteries. This treatment is complex, as well as logistically and technically extremely demanding and must be planned in detail. The visualization of the vascular supply of the liver and the possible parasitic supply of the tumor is essential not only for indication of the procedure and correct identification of the arteries to which the microspheres will be applied, but also for prevention of non-target deposition of radioactive material. This review addresses the use of computed tomographic angiography in the preparatory phase of TARE.

Keywords: Radio-embolization; angiography; computed tomography; liver tumor; review; yttrium-90.

Publication types

  • Review

MeSH terms

  • Computed Tomography Angiography / methods*
  • Embolization, Therapeutic / methods*
  • Hepatic Artery / diagnostic imaging
  • Humans
  • Liver Neoplasms / diagnostic imaging*
  • Liver Neoplasms / therapy
  • Radiopharmaceuticals / therapeutic use*

Substances

  • Radiopharmaceuticals