Bilateral Wilms'Tumor in Trisomy 18 Syndrome: Case Report and Critical Review of the Literature

Ann Clin Lab Sci. 2018 May;48(3):369-372.

Abstract

We present a patient with trisomy 18 syndrome and bilateral Wilms' tumor representing the second case of the literature. Physicians should remain alert to the possibility of WT in patients with trisomy 18 who may survive beyond infancy. In this event, it may be essential to consider periodic abdominal ultrasound for screening purposes. A critical review of the literature is presented.

Keywords: karyotype; nephroblastoma; trisomy 18.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Fatal Outcome
  • Female
  • Humans
  • Infant, Newborn
  • Kidney Neoplasms / etiology
  • Kidney Neoplasms / pathology*
  • Trisomy 18 Syndrome / complications*
  • Wilms Tumor / etiology
  • Wilms Tumor / pathology*