In a general, multimode scattering setup, we show how the permutation symmetry of a many-particle input state determines those scattering unitaries that exhibit strictly suppressed many-particle transition events. We formulate purely algebraic suppression laws that identify these events and show that the many-particle interference at their origin is robust under weak disorder and imperfect indistinguishability of the interfering particles. Finally, we demonstrate that all suppression laws so far described in the literature are embedded in the general framework that we here introduce.