Visceral leishmaniasis in an infant gorilla (Gorilla gorilla gorilla): Clinical signs, diagnosis, and successful treatment with single-dose liposomal amphotericin B

J Med Primatol. 2018 Dec;47(6):416-418. doi: 10.1111/jmp.12354. Epub 2018 Jun 29.

Abstract

A 2-year-old captive gorilla (Gorilla gorilla gorilla) was diagnosed with visceral leishmaniasis in Brazil, and treated with a single dose of liposomal amphotericin B, which resulted in clinical cure. This is the first report of visceral leishmaniasis in gorillas, and the first reported liposomal amphotericin B treatment in great apes.

Keywords: Gorilla gorilla; Leishmania; Western lowland gorilla; amphotericin.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amphotericin B / therapeutic use*
  • Animals
  • Animals, Zoo
  • Antiprotozoal Agents / therapeutic use*
  • Ape Diseases / diagnosis
  • Ape Diseases / drug therapy*
  • Ape Diseases / parasitology
  • Brazil
  • Gorilla gorilla*
  • Leishmaniasis, Visceral / diagnosis
  • Leishmaniasis, Visceral / drug therapy
  • Leishmaniasis, Visceral / parasitology
  • Leishmaniasis, Visceral / veterinary*
  • Male

Substances

  • Antiprotozoal Agents
  • liposomal amphotericin B
  • Amphotericin B