Clinical features and psychological aspects of the decision-making process in stage I testicular germ cell tumors

Future Oncol. 2018 Jul;14(16):1591-1599. doi: 10.2217/fon-2017-0670. Epub 2018 Jun 29.

Abstract

Testicular germ cell tumors (TGCTs) are the most prevalent malignancies in young Caucasian men. Clinical stage I (CSI) TGCTs present the highest cure rate and treatment options after orchiectomy depend on histology and risk factors. Nevertheless, the management of CSI TGCTs is controversial due to the availability of multiple treatments and the lack of randomized trials. An integrated multidisciplinary approach that includes clinicians (surgeons, radiotherapists and oncologists) and psychologists is crucial to maximize the patients' compliance and must be acknowledged with appropriate tools. The aim of our work is to review the oncological and psychological aspects of the decision-making process, discussing the fundamental role of the patient involvement in the personalized management of CSI TGCTs.

Keywords: compliance with treatment; late sequelae; shared decision treatment; stage I germ cell tumors; surveillance.

Publication types

  • Review

MeSH terms

  • Decision Making*
  • Humans
  • Male
  • Neoplasms, Germ Cell and Embryonal / diagnosis
  • Neoplasms, Germ Cell and Embryonal / psychology*
  • Neoplasms, Germ Cell and Embryonal / therapy*
  • Orchiectomy
  • Testicular Neoplasms / diagnosis
  • Testicular Neoplasms / psychology*
  • Testicular Neoplasms / therapy*

Supplementary concepts

  • Testicular Germ Cell Tumor