An Interventional Study of Physical Activity on HbA1C and VO2max in Type 2 Diabetes Mellitus

Indian J Physiol Pharmacol. 2016 Jan-Mar;60(1):76-81.

Abstract

Low cardio-respiratory fitness is prevalent in type 2 diabetics. The objectives of the present study was to assess the effect of an exercise on VO2max and HbA1c in type 2 diabetic patient. The baseline VO2max and HbA1c of 30 diabetics were estimated. VO2max was estimated using the Bruce protocol. HbA1c was measured by ion-exchange chromatography with Bio-Rad D10. After an exercise regimen for a period of 6 months, they returned to check their VO2max and HbA1c. The baseline VO2max was 32.67±11.99 ml/kg/min (low for given age) and HbA1C% values were high (7.58±1.66). After walking it was found that VO2max increased and HbA1c decreased significantly. Exercise improves cardiorespiratory fitness and lower HbA1c. So, a suitable exercise should be incorporated along with diet and drug prescription.

MeSH terms

  • Aerobiosis
  • Diabetes Mellitus, Type 2 / metabolism*
  • Exercise*
  • Glycated Hemoglobin / metabolism*
  • Humans
  • Oxygen Consumption / physiology*

Substances

  • Glycated Hemoglobin A
  • hemoglobin A1c protein, human