Carcinoma in situ within an area of Barrett esophagus in a dog with megaesophagus

J Vet Diagn Invest. 2018 Sep;30(5):752-754. doi: 10.1177/1040638718786330. Epub 2018 Jun 28.

Abstract

A 10-y-old Irish Setter was presented with a history of recurrent episodes of regurgitation and vomiting, with more recent development of tachypnea. Megaesophagus had been diagnosed in the dog 2 y prior to this presentation. A solitary polypoid mass present immediately rostral to the lower esophageal sphincter was biopsied during percutaneous endoscopic gastrostomy tube placement. Barrett esophagus was diagnosed based on the observation of a polypoid mass with intestinal metaplasia that arose from the surrounding esophagus. Histology of the polypoid mass demonstrated squamous-to-columnar metaplasia, hyperplasia, dysplasia, and carcinoma in situ.

Keywords: Canine; esophagitis; gastroesophageal reflux disease; intestinal metaplasia; regurgitation.

Publication types

  • Case Reports

MeSH terms

  • Animals
  • Barrett Esophagus / diagnosis
  • Barrett Esophagus / veterinary*
  • Biopsy / veterinary
  • Carcinoma in Situ / diagnosis
  • Carcinoma in Situ / veterinary*
  • Diagnosis, Differential
  • Dog Diseases / diagnosis*
  • Dog Diseases / pathology
  • Dogs
  • Esophageal Neoplasms / diagnosis
  • Esophageal Neoplasms / veterinary*
  • Fatal Outcome
  • Gastroesophageal Reflux / veterinary*
  • Male
  • Neoplasms, Multiple Primary / diagnosis
  • Neoplasms, Multiple Primary / veterinary*