New headaches with normal inflammatory markers: an early atypical presentation of giant cell arteritis

BMJ Case Rep. 2018 Jun 27:2018:bcr2017223240. doi: 10.1136/bcr-2017-223240.

Abstract

An 80-year-old man presented repeatedly to his general practitioner with 3 months of unexplained persistent frontal headaches. CT head revealed no diagnosis. His dentist diagnosed his co-existing jaw pain as bruxism. Three months later, the patient happened to attend a routine ophthalmology follow-up appointment. During this routine appointment, features of giant cell arteritis (GCA) including worrying visual complications were first noted. His inflammatory markers (C-reactive protein and erythrocyte sedimentation rate) were not significantly raised-contrary to the norm. A temporal artery ultrasound and biopsy were performed, in light of the history. This confirmed GCA. He was commenced on high-dose oral prednisolone and was managed by ophthalmology and rheumatology. At 4 weeks, symptoms resolved with no permanent visual loss despite a prolonged initial symptomatic period. Multiple symptomatic presentations to different specialties should therefore alert clinicians to a unifying diagnosis, for example, vasculitis. Serious illnesses may present with severe symptoms despite normal screening investigations.

Keywords: headache (including migraines); neuroopthalmology; vasculitis.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Blood Sedimentation
  • C-Reactive Protein / analysis
  • Giant Cell Arteritis / complications*
  • Giant Cell Arteritis / diagnosis
  • Headache / diagnosis
  • Headache / etiology*
  • Humans
  • Incidental Findings
  • Male
  • Vision Disorders / diagnosis
  • Vision Disorders / etiology*

Substances

  • C-Reactive Protein