Behavioral interventions in health neuroscience

Ann N Y Acad Sci. 2018 Sep;1428(1):51-70. doi: 10.1111/nyas.13913. Epub 2018 Jun 26.

Abstract

Many chronic health concerns (obesity, addiction, stress, chronic pain, and depression) have garnered recent attention for their increasing frequency, intractability, and serious health consequences. Because they are often difficult to treat and there are not always effective pharmacological treatments, many patients are pursuing behavioral interventions for these conditions. Experimental behavioral intervention studies have shown some efficacy for health, but the mechanisms for these treatments are not well understood. Health neuroscience is a burgeoning field that seeks to link neural function and structure with physical and mental health. Through this lens, initial studies have begun to investigate how behavioral interventions modulate neural function in ways that lead to improvements in health markers and outcomes. Here, we provide a review of these studies in terms of how they modulate key neurobiological systems, and how modulation of these systems relates to physical health and disease outcomes. We conclude with discussion of opportunities for future research in this promising area of study.

Keywords: health outcomes; interventions; neural systems; neuroscience.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Behavior Therapy*
  • Brain Mapping
  • Chronic Disease / psychology
  • Chronic Disease / therapy*
  • Chronic Pain / physiopathology
  • Chronic Pain / therapy
  • Cognitive Behavioral Therapy
  • Connectome
  • Emotions
  • Frontal Lobe / physiopathology
  • Health Status
  • Humans
  • Limbic System / physiopathology
  • Nerve Net / physiology
  • Neurosciences / trends*
  • Prefrontal Cortex / physiopathology
  • Reward
  • Self-Control
  • Stress, Psychological / physiopathology