Brain derived neurotropic factor single nucleotide polymorphism Val66Met and serum protein levels are associated with development of vincristine-induced peripheral neuropathy in patients with lymphoma

David Azoulay; Roni Nasser; Rivka Sharon; Liya Simanovich; Luiza Akria; Ety Shaoul; Netanel A Horowitz

doi:10.1111/bjh.15428

Brain derived neurotropic factor single nucleotide polymorphism Val66Met and serum protein levels are associated with development of vincristine-induced peripheral neuropathy in patients with lymphoma

Br J Haematol. 2019 Apr;185(1):175-177. doi: 10.1111/bjh.15428. Epub 2018 Jun 25.

Authors

David Azoulay¹, Roni Nasser², Rivka Sharon¹, Liya Simanovich¹, Luiza Akria¹, Ety Shaoul¹, Netanel A Horowitz²

Affiliations

¹ Haematology Unit and Laboratories, Galilee Medical Centre, Naharia& Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.
² Department of Haematology and Bone Marrow Transplantation, Rambam Health Care Campus, Haifa, Israel.

PMID: 29938784
DOI: 10.1111/bjh.15428

No abstract available

Keywords: BDNF single nucleotide polymorphism (Val66Met-SNP); brain-derived neurotrophic factor (BDNF); non-Hodgkin lymphoma (NHL); vincristine-induced peripheral neuropathy (VIPN).

Publication types

Letter

MeSH terms

Alleles
Amino Acid Substitution*
Brain-Derived Neurotrophic Factor / blood*
Brain-Derived Neurotrophic Factor / genetics*
Disease Susceptibility
Female
Genotype
Humans
Lymphoma / complications*
Lymphoma / drug therapy
Lymphoma / genetics*
Male
Peripheral Nervous System Diseases / etiology*
Polymorphism, Single Nucleotide*
Vincristine / adverse effects*
Vincristine / therapeutic use

Substances

Brain-Derived Neurotrophic Factor
Vincristine