Why is the hydrolytic activity of acetylcholinesterase pH dependent? Kinetic study of acetylcholine and acetylthiocholine hydrolysis catalyzed by acetylcholinesterase from electric eel

Z Naturforsch C J Biosci. 2018 Sep 25;73(9-10):345-351. doi: 10.1515/znc-2017-0134.

¹ Department of Physical Chemistry, Faculty of Chemical Technology, University of Pardubice, Studentská 573, 532 10 Pardubice, Czech Republic.
² Department of Physical Chemistry, Faculty of Chemical Technology, University of Pardubice, Studentská 573, 532 10 Pardubice, Czech Republic, Fax: +420-466-037-068.
³ Department of Biological and Biochemical Sciences, Faculty of Chemical Technology, University of Pardubice, Studentská 573, 523 10 Pardubice, Czech Republic.

No abstract available

Keywords: acetylcholinesterase; enzyme activity; kinetics; pH dependence.

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