Efficient production of succinic acid from herbal extraction residue hydrolysate

Caixia Wang; Xinyao Su; Wei Sun; Sijing Zhou; Junyu Zheng; Mengting Zhang; Mengchu Sun; Jianping Xue; Xia Liu; Jianmin Xing; Shilin Chen

doi:10.1016/j.biortech.2018.06.041

Efficient production of succinic acid from herbal extraction residue hydrolysate

Bioresour Technol. 2018 Oct:265:443-449. doi: 10.1016/j.biortech.2018.06.041. Epub 2018 Jun 15.

Authors

Caixia Wang¹, Xinyao Su², Wei Sun¹, Sijing Zhou³, Junyu Zheng¹, Mengting Zhang⁴, Mengchu Sun⁵, Jianping Xue⁵, Xia Liu⁶, Jianmin Xing⁷, Shilin Chen⁸

Affiliations

¹ Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, No. 16, Nanxiaojie, Dongzhimennei, Beijing 100700, PR China.
² Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, No. 16, Nanxiaojie, Dongzhimennei, Beijing 100700, PR China; School of Life Science, Huai Bei Normal University, Huaibei 23500, PR China.
³ Beijing Radiation Center, Beijing 100015, PR China.
⁴ Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, No. 16, Nanxiaojie, Dongzhimennei, Beijing 100700, PR China; School of Chemistry, Chemical Engineering and Life Science, Wuhan University of Technology, Wuhan 430070, PR China.
⁵ School of Life Science, Huai Bei Normal University, Huaibei 23500, PR China.
⁶ School of Chemistry, Chemical Engineering and Life Science, Wuhan University of Technology, Wuhan 430070, PR China.
⁷ National Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, PR China.
⁸ Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, No. 16, Nanxiaojie, Dongzhimennei, Beijing 100700, PR China. Electronic address: slchen@icmm.ac.cn.

PMID: 29935453
DOI: 10.1016/j.biortech.2018.06.041

Abstract

In this study, six different herbal-extraction residues were evaluated for succinic acid production in terms of chemical composition before and after dilute acid pretreatment (DAP) and sugar release performance. Chemical composition showed that pretreated residues of Glycyrrhiza uralensis Fisch (GUR) and Morus alba L. (MAR) had the highest cellulose content, 50% and 52%, respectively. Higher concentrations of free sugars (71.6 g/L total sugar) and higher hydrolysis yield (92%) were both obtained under 40 FPU/g DM at 10% solid loading for GUR. Using scanning electron microscopy (SEM), GUR was found to show a less compact structure due to process of extraction. Specifically, the fibers in pretreated GUR were coarse and disordered compared with that of GUR indicated by SEM. Finally, 65 g/L succinic acid was produced with a higher yield of 0.89 g/g total sugar or 0.49 g/g GUR. Our results illustrate the potential of GUR for succinic acid production.

Keywords: Biomass; Herbal-extraction residues; Succinic acid.

MeSH terms

Carbohydrate Metabolism*
Carbohydrates
Cellulose
Fermentation*
Hydrolysis
Succinic Acid / chemical synthesis*

Substances

Carbohydrates
Cellulose
Succinic Acid