Bladder Mucosal Graft Vaginoplasty: A Case Report

J Pediatr Adolesc Gynecol. 2018 Oct;31(5):528-532. doi: 10.1016/j.jpag.2018.06.003. Epub 2018 Jun 19.

Abstract

Background: Female vaginoplasty reconstruction, by choice, is usually performed with adjacent tissue. However in some clinical conditions such as high urogenital confluence sinus, cloacal malformation with extreme vaginal hypoplasia, local tissue may not be available. When vaginal replacement is performed in pediatric patients intestinal segments is preferred to non-operative procedures that require continuative dilations. However mucus production, malignant transformation risk and diversion colitis are important side effects.

Technique: We present a nouvel technique for vaginoplasty in a female child presenting with an isolated urogenital sinus malformation without virilization. The patient at 20 months underwent vaginoplasty using tubularized bladder mucosal graft.

Results: Surgical procedure was devoid of complications. Pubertal development occurred at age of 15. She underwent regular follow up until 18 years of age. At this age we performed clinical evaluation: absence of vaginal introitus stenosis and good cosmetic results were observed. Then she underwent vaginoscopy with multiple biopsies. Pathology examination of the bladder mucosal graft evidenced a normal structure of the mucosa, with a stratified squamous epithelium.

Discussion: Different techniques are taken into account for vaginal reconstruction according to the severity and to the type of malformation. We describe the use of bladder mucosal graft with favorable results after long term follow-up.

Keywords: Bladder mucosa; DSD; Graft; Urogenital sinus; Vaginoplasty.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Female
  • Gynecologic Surgical Procedures / methods*
  • Humans
  • Infant
  • Infant, Newborn
  • Mucous Membrane / transplantation
  • Treatment Outcome
  • Urinary Bladder / transplantation*
  • Urogenital Abnormalities / surgery*
  • Vagina / abnormalities*
  • Vagina / surgery