On a Western diet, APOEɛ4 is associated with low innate immune sensing, but not APOEɛ3

J Allergy Clin Immunol. 2018 Oct;142(4):1346-1349.e9. doi: 10.1016/j.jaci.2018.05.033. Epub 2018 Jun 19.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute-Phase Proteins / metabolism
  • Alkaline Phosphatase / metabolism
  • Animals
  • Apolipoprotein E3 / genetics*
  • Apolipoprotein E4 / genetics*
  • Carrier Proteins / metabolism
  • Diet, Western*
  • Feces / chemistry
  • Female
  • Genotype
  • Humans
  • Immunity, Innate*
  • Lipopolysaccharide Receptors / metabolism
  • Liver / enzymology
  • Male
  • Membrane Glycoproteins / metabolism
  • Mice
  • Toll-Like Receptors / blood*

Substances

  • Acute-Phase Proteins
  • Apolipoprotein E3
  • Apolipoprotein E4
  • Carrier Proteins
  • Lipopolysaccharide Receptors
  • Membrane Glycoproteins
  • Toll-Like Receptors
  • lipopolysaccharide-binding protein
  • Alkaline Phosphatase