Optimization and characterization of lambda-cyhalothrin solid nanodispersion by self-dispersing method

Pest Manag Sci. 2019 Feb;75(2):380-389. doi: 10.1002/ps.5122. Epub 2018 Sep 21.

Abstract

Background: Pesticide is an important agricultural necessity to control plant diseases and pests, ensuring safe production of food. However, the low efficacy, large dosage and high-frequency use of conventional pesticide formulation seriously induced food safety and ecological environment issues. In this research, lambda-cyhalothrin solid nanodispersion (LCSND) was developed by a self-dispersing method.

Results: The mean particle size of the lambda-cyhalothrin solid nanodispersion was 32.7 ± 1.1 nm. It exhibited excellent dispersibility, wettability and stability, especially the improved bioavailability compared to the commercial formulations. Notably, the solid nanodisperison had a small particle size and large specific surface area. The solid nanodispersion without organic solvents can minimize the environment pollution and overcome the instability characteristic of the liquid formulations.

Conclusion: Therefore, lambda-cyhalothrin solid nanodispersion has broad application prospects in agricultural production and environmental protection. © 2018 Society of Chemical Industry.

Keywords: lambda-cyhalothrin; pesticide; self-dispersing; solid nanodispersion.

MeSH terms

  • Biological Availability
  • Fungicides, Industrial / chemistry*
  • Insect Control / instrumentation
  • Insecticides / chemistry*
  • Nanoparticles / chemistry*
  • Nitriles / chemistry*
  • Particle Size*
  • Pest Control / instrumentation*
  • Pyrethrins / chemistry*
  • Solubility
  • Wettability

Substances

  • Fungicides, Industrial
  • Insecticides
  • Nitriles
  • Pyrethrins
  • cyhalothrin