Susceptibility of Chikungunya Virus to Inactivation by Heat and Commercially and World Health Organization-Recommended Biocides

Sergej Franz; Martina Friesland; Vânia Passos; Daniel Todt; Graham Simmons; Christine Goffinet; Eike Steinmann

doi:10.1093/infdis/jiy359

Susceptibility of Chikungunya Virus to Inactivation by Heat and Commercially and World Health Organization-Recommended Biocides

J Infect Dis. 2018 Sep 22;218(9):1507-1510. doi: 10.1093/infdis/jiy359.

Authors

Sergej Franz¹, Martina Friesland¹, Vânia Passos^{1

2}, Daniel Todt^{1

3}, Graham Simmons^{4

5}, Christine Goffinet¹, Eike Steinmann^{1

3}

Affiliations

¹ Institute of Experimental Virology, TWINCORE Centre for Experimental and Clinical Infection Research (a joint venture between the Medical School Hannover and the Helmholtz Centre for Infection Research), Hannover, Germany.
² Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, Portugal.
³ Department of Molecular and Medical Virology, Ruhr-University Bochum, Germany.
⁴ Blood Systems Research Institute, San Francisco, California.
⁵ Department of Laboratory Medicine, University of California, San Francisco.

Abstract

Despite increasing clinical relevance of Chikungunya virus (CHIKV) infection, caused by a rapidly emerging pathogen, recommended guidelines for its inactivation do not exist. In this study, we investigated the susceptibility of CHIKV to inactivation by heat and commercially available hand, surface, and World Health Organization-recommended disinfectants to define CHIKV prevention protocols for healthcare systems.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Cell Line
Chikungunya Fever / prevention & control*
Chikungunya virus / drug effects*
Disinfectants / pharmacology*
HEK293 Cells
Hot Temperature
Humans
World Health Organization

Substances

Disinfectants