Perioperative Glucocorticoid Treatment of Soft Tissue Reconstruction in Patients on Long-term Steroid Therapy: The Experience of 6 Cases Using Reversed Posterior Interosseous Flap for Hand Neoplasm Surgery

Ann Plast Surg. 2018 Sep;81(3):302-304. doi: 10.1097/SAP.0000000000001534.

Abstract

Introduction: Long-term steroid therapy is associated with increased postoperative morbidity. Whether to use a stress dose of glucocorticoids (GCs) in surgical patients remains controversial. In the present study, we reported our experience in perioperative GC treatment of 6 patients on long-term steroid therapy for autoimmune diseases undergoing hand reconstruction using reversed interosseous flap.

Methods: The reversed interosseous flap reconstructions were performed after local extended resection of hand neoplasms. The patients were all diagnosed with autoimmune diseases and were undergoing long-term steroid therapy. Stress dose of GCs was not given in any case, and all the patients either remained on their baseline maintenance dose or decreased the dose until the morning of the operation day. Hypotension, water-electrolyte imbalance, hypoglycemia, and other symptoms of adrenal insufficiency were carefully assessed. Appearances of flap complications were recorded.

Results: None of the patients developed hypotension or other symptomatic adrenal insufficiency. Flap infection, venous congestion, or complete or partial loss of flap was not observed in any patient. Effusion underneath the flap was developed in only 1 case and was solved by proper drainage.

Conclusions: It is safe, reliable, and versatile to use reversed interosseous flap to repair hand defects in patients on long-term steroid therapy. A stress dose of GCs might not be necessary in this procedure and other equally moderate soft tissue reconstructive surgeries.

MeSH terms

  • Adult
  • Aged
  • Anti-Inflammatory Agents / administration & dosage*
  • Anti-Inflammatory Agents / therapeutic use
  • Autoimmune Diseases / complications
  • Autoimmune Diseases / drug therapy*
  • Carcinoma, Basal Cell / complications
  • Carcinoma, Basal Cell / surgery
  • Carcinoma, Squamous Cell / complications
  • Carcinoma, Squamous Cell / surgery
  • Drug Administration Schedule
  • Female
  • Follow-Up Studies
  • Glucocorticoids / administration & dosage*
  • Glucocorticoids / therapeutic use
  • Hand / surgery*
  • Humans
  • Male
  • Middle Aged
  • Perioperative Care / methods*
  • Plastic Surgery Procedures / methods*
  • Postoperative Complications / immunology
  • Postoperative Complications / prevention & control
  • Skin Neoplasms / complications
  • Skin Neoplasms / surgery
  • Soft Tissue Neoplasms / complications
  • Soft Tissue Neoplasms / surgery
  • Surgical Flaps*
  • Treatment Outcome

Substances

  • Anti-Inflammatory Agents
  • Glucocorticoids