Expression of immune genes RIG-I and Mx in mallard ducks infected with low pathogenic avian influenza (LPAI): A dataset

Anu S Helin; Michelle Wille; Clara Atterby; Josef Järhult; Jonas Waldenström; Joanne R Chapman

doi:10.1016/j.dib.2018.04.061

Expression of immune genes RIG-I and Mx in mallard ducks infected with low pathogenic avian influenza (LPAI): A dataset

Data Brief. 2018 Apr 23:18:1562-1566. doi: 10.1016/j.dib.2018.04.061. eCollection 2018 Jun.

Authors

Anu S Helin¹, Michelle Wille¹, Clara Atterby², Josef Järhult³, Jonas Waldenström¹, Joanne R Chapman^{1

4}

Affiliations

¹ Centre for Ecology and Evolution in Microbial Model Systems, Linnaeus University, Kalmar, Sweden.
² Zoonosis Science Centre, Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.
³ Section for Infectious Diseases, Department of Medical Sciences, Uppsala University, Uppsala, Sweden.
⁴ Department of Molecular Biosciences, University of Kansas, Lawrence, USA.

Abstract

This article provides data on primer sequences used to amplify the innate immune genes RIG-I and Mx and a set of normalizing reference genes in mallards (Anas platyrhynchos), and shows which reference genes are stable, per tissue, for our experimental settings. Data on the expressional changes of these two genes over a time-course of infection with low pathogenic avian influenza virus (LPAI) are provided. Individual-level data are also presented, including LPAI infection load, and per tissue gene expression of RIG-I and Mx. Gene expression in two outlier individuals is explored in more depth.