Data on the gut and saliva microbiota from a cohort of atherosclerosis patients determined by 16S rRNA gene sequencing

Gregory B Gloor; Ruth Grace Wong; Emma Allen-Vercoe; Vincent Dinculescu; Michael Pignanelli; Chrysi Bogiatzi; Gregor Reid; J David Spence

doi:10.1016/j.dib.2018.05.032

Data on the gut and saliva microbiota from a cohort of atherosclerosis patients determined by 16S rRNA gene sequencing

Data Brief. 2018 May 11:19:481-485. doi: 10.1016/j.dib.2018.05.032. eCollection 2018 Aug.

Authors

Gregory B Gloor¹, Ruth Grace Wong¹, Emma Allen-Vercoe², Vincent Dinculescu³, Michael Pignanelli⁴, Chrysi Bogiatzi⁵, Gregor Reid⁶, J David Spence⁷

Affiliations

¹ Dept. Biochemistry, Schulich School of Medicine and Dentistry, Western University, London, Canada.
² Dept. Molecular and Cell Biology, University of Guelph, Guelph, Canada.
³ Now at Department of Radiology, University of Calgary, Calgary, Canada.
⁴ Schulich School of Medicine and Dentistry, CIHR Summer Research Training Program, Canada.
⁵ Now at Dept. of Neurology, McMaster University, Hamilton, Canada.
⁶ Depts. of Urology and Microbiology, Schulich School of Medicine and Dentistry, Western University, and Lawson Research Institute, London, Canada.
⁷ Stroke Prevention & Atherosclerosis Research Centre, Robarts Research Institute, Western University, London, Canada.

Abstract

This work was conducted to characterize the 16S rRNA gene profile of a cohort of patients with traditional risk factors for developing atherosclerosis. The patients in the cohort were divided into two extremes; those predicted to develop extreme atherosclerosis who did not (Protected), and those predicted not to develop atherosclerosis who did (Unexplained). Bacterial DNA was isolated from stool and saliva and this was used to determine the V4 variable region of the 16S rRNA gene sequence composition of the samples in triplicate.