Electroactive poly(sulfobetaine-3,4-ethylenedioxythiophene) (PSBEDOT) with controllable antifouling and antimicrobial properties

Bin Cao; Chen-Jung Lee; Zhipeng Zeng; Fang Cheng; Fujian Xu; Hongbo Cong; Gang Cheng

doi:10.1039/c5sc03887a

Electroactive poly(sulfobetaine-3,4-ethylenedioxythiophene) (PSBEDOT) with controllable antifouling and antimicrobial properties

Chem Sci. 2016 Mar 1;7(3):1976-1981. doi: 10.1039/c5sc03887a. Epub 2015 Dec 18.

Authors

Bin Cao¹, Chen-Jung Lee¹, Zhipeng Zeng¹, Fang Cheng², Fujian Xu³, Hongbo Cong¹, Gang Cheng¹

Affiliations

¹ Department of Chemical and Biomolecular Engineering , University of Akron , Akron , Ohio 44325 , USA . Email: gc@uakron.edu ; http://gozips.uakron.edu/∼gc/index.html ; Email: hcong@uakron.edu.
² School of Pharmaceutical Engineering , Dalian University of Technology , Dalian , Liaoning Province 116024 , China.
³ Key Laboratory of Carbon Fiber and Functional Polymers (Beijing University of Chemical Technology) , Ministry of Education , Beijing Laboratory of Biomedical Materials , Beijing University of Chemical Technology , Beijing 100029 , China.

Abstract

This paper reports a multifunctional zwitterionic poly(sulfobetaine-3,4-ethylenedioxythiophene) (PSBEDOT), which could be facilely synthesized by electropolymerization in aqueous solution. The PSBEDOT surface exhibits excellent conductivity, stability and switchable antifouling/antimicrobial properties. It shows great promise for applications in organic bioelectronics. This new material may significantly increase the performance and service life, minimize the foreign body reaction, improve the biocompatibility and reduce the infection of bio-electronic devices.