Restoration of pyrethroid susceptibility in a highly resistant Aedes aegypti population

Biol Lett. 2018 Jun;14(6):20180022. doi: 10.1098/rsbl.2018.0022.

Abstract

Insecticide resistance has evolved in disease vectors worldwide, creating the urgent need to either develop new control methods or restore insecticide susceptibility to regain use of existing tools. Here we show that phenotypic susceptibility can be restored in a highly resistant field-derived strain of Aedes aegypti in only 10 generations through rearing them in the absence of insecticide.

Keywords: Aedes aegypti; insecticide resistance; kdr; pyrethroids.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Aedes / drug effects
  • Aedes / genetics*
  • Animals
  • Female
  • Insecticide Resistance / genetics*
  • Insecticides / pharmacology*
  • Male
  • Mosquito Vectors / genetics
  • Mutation
  • Phenotype
  • Pyrethrins / pharmacology*

Substances

  • Insecticides
  • Pyrethrins

Associated data

  • Dryad/10.5061/dryad.33n9p
  • figshare/10.6084/m9.figshare.c.4114523