Infant botulism: Two case reports and electroneuromyogram findings

J Bernardor; J Neveu; H Haas; G Pitelet; M-R Popoff; C Mazuet; E Bérard; C Boulay; B Chabrol

doi:10.1016/j.arcped.2018.05.002

Infant botulism: Two case reports and electroneuromyogram findings

Arch Pediatr. 2018 Jun 7:S0929-693X(18)30108-8. doi: 10.1016/j.arcped.2018.05.002. Online ahead of print.

Authors

J Bernardor¹, J Neveu², H Haas¹, G Pitelet¹, M-R Popoff³, C Mazuet³, E Bérard⁴, C Boulay⁵, B Chabrol⁵

Affiliations

¹ Hôpitaux pédiatriques de Nice CHU, Lenval, 57, avenue de la Californie, 06200 Nice, France.
² Hôpitaux pédiatriques de Nice CHU, Lenval, 57, avenue de la Californie, 06200 Nice, France. Electronic address: neveu.julien@gmail.com.
³ Unité des bactéries anaérobies et toxines, Institut Pasteur, 25, rue du Dr-Roux, 75724 Paris cedex 15, France.
⁴ Hôpital de l'Archet, CHU de Nice, 151, route de St-Antoine, 06200 Nice, France.
⁵ Service de neuropédiatrie, hôpital La Timone-Enfants, AP-HM, 264, rue St-Pierre, 13385 Marseille cedex 5, France.

PMID: 29887515
DOI: 10.1016/j.arcped.2018.05.002

Abstract

Botulism is an uncommon severe neuromuscular disorder. We report two recent cases of confirmed infant botulism diagnosed in an 11-week and a 5-month-old infant along with electroneuromyogram (ENMG) findings. Then, we discuss the EMG features of infant botulism. In severe forms of infant botulism, presence of these features might help decide to use botulinum immune globulin. To our knowledge, case 1 is the first case reported in France based on confirmed dust contamination.

Keywords: Botulinum toxin; Botulism; Electromyography; Infant.