A mind full of self: Self-referential processing as a mechanism underlying the therapeutic effects of mindfulness training on internalizing disorders

Neurosci Biobehav Rev. 2018 Sep:92:172-186. doi: 10.1016/j.neubiorev.2018.06.007. Epub 2018 Jun 8.

Abstract

The aim of the current review is to advance the hypothesis that change in self-referential processing is a key but under-examined mechanism through which mindfulness training confers its therapeutic benefits for individuals with internalizing disorders. Consequently, we integrated neuroscientific studies on aberrant self-referential processing in internalizing disorders with contemplative science scholarship examining the effects of mindfulness training on the self-referential system. Reviewing these literatures yielded four major conclusions: (1) internalizing disorders can be characterized by excessive self-referential processing and emotion dysregulation; (2) mindfulness training has moderate effects on reducing internalizing symptoms; (3) mindfulness training promotes the shifting from narrative self-focus to present-centered experiential awareness; (4) such mindfulness-induced changes in self-reference is accompanied by reduced activation in overactive self-referential brain regions that have been implicated in internalizing disorders. Clinical and research implications related to delineating the role of self-referential processing in producing the therapeutic effects of mindfulness training are discussed.

Keywords: Internalizing disorders; Mindfulness; Self-Referential processing.

Publication types

  • Review

MeSH terms

  • Affective Symptoms / psychology*
  • Affective Symptoms / rehabilitation*
  • Awareness / physiology*
  • Humans
  • Mindfulness / methods*
  • Self Concept*