Covalent bonding of Schiff base network-1 as a stationary phase for capillary electrochromatography

Nengsheng Ye; Xuan Wang; Qingye Liu; Xiaoyu Hu

doi:10.1016/j.aca.2018.04.037

Covalent bonding of Schiff base network-1 as a stationary phase for capillary electrochromatography

Anal Chim Acta. 2018 Oct 22:1028:113-120. doi: 10.1016/j.aca.2018.04.037. Epub 2018 Apr 18.

Authors

Nengsheng Ye¹, Xuan Wang², Qingye Liu², Xiaoyu Hu²

Affiliations

¹ Department of Chemistry, Capital Normal University, Beijing, 100048, PR China. Electronic address: yensh@cnu.edu.cn.
² Department of Chemistry, Capital Normal University, Beijing, 100048, PR China.

PMID: 29884348
DOI: 10.1016/j.aca.2018.04.037

Abstract

Covalent organic frameworks (COFs), featuring low densities, high surface areas, and good thermal and chemical stabilities, are gradually attracting interest in the field of analytical chemistry. A type of microporous polymer network material named Schiff base network-1 (SNW-1) was introduced into a capillary column through covalent bonding. The obtained SNW-1-coated capillary column was characterized by thermogravimetric analysis, scanning electron microscopy, Fourier transform infrared spectroscopy, and X-ray diffraction. Then, the SNW-1-coated capillary column was successfully utilized for the open-tubular capillary electrochromatography (OT-CEC) separation of sulfonamides, cephalosporins, amino acids and parabens. The fabricated capillary column showed good separation efficiency (R_s > 1.4), stability and reproducibility (relative standard deviation (RSD) < 5.88%). To the best of our knowledge, this is the first report of a covalent bonding strategy to bond an SNW material to a capillary column for OT-CEC.

Keywords: Covalent bonding; Covalent organic frameworks; Open-tubular capillary electrochromatography; Schiff base networks; Stationary phase.