Commentary article based on the original research article by Li Y, He L, Dong H et al. Fever-inspired immunotherapy based on photothermal CpG nanotherapeutics: the critical role of mild heat in regulating tumor microenvironment. Advanced Science 1700805, 1-12 (2018).
Keywords: CpG; adjuvant; hyperthermia; innate immunity; nanovaccine; tumor microenvironment.