The AAA Risk Factors Scale: A New Model to Screen for the Risk of Asthma, Allergic Rhinitis and Atopic Dermatitis in Children

Med Princ Pract. 2018;27(5):472-480. doi: 10.1159/000490704. Epub 2018 Jun 7.

Abstract

Objective: To create an allergic disease risk factors scale score that would screen for the risk assessment of asthma, allergic rhinitis and atopic dermatitis (AD) in children from 3 to 17 years.

Methods: This case-control study, conducted between December 2015 and April 2016, enrolled 1,274 children. The allergic disease risk factors scale was created by combining environmental, exposure to toxics during pregnancy and breastfeeding and parental history of allergic diseases.

Results: Playing on carpets, male gender, child's respiratory problems or history of eczema before the age of 2 years, and humidity significantly increased the odds of allergies in the child. Maternal waterpipe smoking, maternal history of rhinitis, history of asthma in the mother or the father, along with the maternal drug intake or alcohol consumption during pregnancy significantly increased the odds of allergies in the child. There was a significant increase in allergy diseases per category of the allergic disease risk factors scale (p < 0.001 for trend). Scores ≤2.60 best represented control individuals, while scores > 5.31 best represented children with allergic diseases.

Conclusion: Allergic diseases seem to be linked to several risk factors in our population of school children. Many environmental factors might be incriminated in these allergic diseases.

Keywords: Allergic disease; Allergic rhinitis; Asthma; Atopic dermatitis; Children; Eczema; Humidity; Screening.

MeSH terms

  • Adolescent
  • Asthma / epidemiology
  • Asthma / etiology*
  • Case-Control Studies
  • Child
  • Child, Preschool
  • Cross-Sectional Studies
  • Dermatitis, Atopic / epidemiology
  • Dermatitis, Atopic / etiology*
  • Environmental Exposure / adverse effects
  • Female
  • Humans
  • Lebanon / epidemiology
  • Male
  • Parents
  • Pregnancy
  • Prenatal Exposure Delayed Effects
  • ROC Curve
  • Rhinitis, Allergic / epidemiology
  • Rhinitis, Allergic / etiology*
  • Risk Assessment / methods*
  • Risk Factors
  • Smoking / adverse effects
  • Surveys and Questionnaires