Insights into recombination-like events leading to outbreaks in USA through a retrospective study of porcine epidemic diarrhea virus isolates from China

Infect Genet Evol. 2018 Sep:63:216-218. doi: 10.1016/j.meegid.2018.06.002. Epub 2018 Jun 4.

Abstract

In April 2013, severe porcine epidemic diarrhea (PED) outbreaks first appeared in USA, causing significant financial losses. To detect the geographic origin and timing of USA porcine epidemic diarrhea virus (PEDV) isolates, we conducted a retrospective study to isolate 19 PEDV strains from positive samples obtained prior to April 2013. The results of phylogenetic and recombination analyses showed that GDS10 strain shared a common ancestor with CO13 strain, which was obtained from a piglet with severe diarrhea in USA.

Keywords: Chinese isolate; Origin; Porcine epidemic diarrhea virus; Recombination.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • China / epidemiology
  • Coronavirus Infections / epidemiology
  • Coronavirus Infections / transmission
  • Coronavirus Infections / veterinary*
  • Coronavirus Infections / virology
  • Disease Outbreaks*
  • Epidemiological Monitoring / veterinary*
  • Feces / virology
  • Molecular Epidemiology
  • Phylogeny*
  • Porcine epidemic diarrhea virus / classification
  • Porcine epidemic diarrhea virus / genetics*
  • Porcine epidemic diarrhea virus / isolation & purification
  • Porcine epidemic diarrhea virus / pathogenicity
  • Recombination, Genetic
  • Retrospective Studies
  • Swine
  • Swine Diseases / epidemiology*
  • Swine Diseases / transmission
  • Swine Diseases / virology
  • United States / epidemiology