Production of early and late nuclear DNA damage and extracellular 8-oxodG in normal human skin fibroblasts after carbon ion irradiation compared to X-rays

Toxicol In Vitro. 2018 Oct:52:116-121. doi: 10.1016/j.tiv.2018.06.004. Epub 2018 Jun 4.
No abstract available

Keywords: 8-oxodG; Carbon ions; DNA damage; Oxidative stress; Skin.

Publication types

  • Comparative Study

MeSH terms

  • 8-Hydroxy-2'-Deoxyguanosine
  • Carbon*
  • Cells, Cultured
  • DNA Damage*
  • Deoxyguanosine / analogs & derivatives*
  • Deoxyguanosine / metabolism
  • Fibroblasts / metabolism
  • Fibroblasts / radiation effects*
  • Heavy Ions*
  • Humans
  • Micronuclei, Chromosome-Defective*
  • Micronucleus Tests
  • Skin / cytology
  • X-Rays*
  • Young Adult

Substances

  • Carbon
  • 8-Hydroxy-2'-Deoxyguanosine
  • Deoxyguanosine