Dataset of mitochondrial genome variants in oncocytic tumors

Lihua Lyu; Qiufeng Wang; Shujie Song; Huaibin Zhou; Ming Li; Chen Zhou; Zhiying Jiang; Liyan Li; Jianxin Lyu; Guorong Chen; Yidong Bai

doi:10.1016/j.dib.2018.02.040

Dataset of mitochondrial genome variants in oncocytic tumors

Data Brief. 2018 Feb 16:17:1149-1152. doi: 10.1016/j.dib.2018.02.040. eCollection 2018 Apr.

Authors

Lihua Lyu¹, Qiufeng Wang¹, Shujie Song¹, Huaibin Zhou¹, Ming Li¹, Chen Zhou¹, Zhiying Jiang¹, Liyan Li², Jianxin Lyu¹, Guorong Chen², Yidong Bai^{1

3}

Affiliations

¹ School of Laboratory Medicine and Life Sciences, Key Laboratory of Laboratory Medicine, Ministry of Education, Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical University, Wenzhou 325035, Zhejiang, China.
² Department of Pathology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.
³ Department of Cellular and Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.

Abstract

This dataset presents the mitochondrial genome variants associated with oncocytic tumors. These data were obtained by Sanger sequencing of the whole mitochondrial genomes of oncocytic tumors and the adjacent normal tissues from 32 patients. The mtDNA variants are identified after compared with the revised Cambridge sequence, excluding those defining haplogroups of our patients. The pathogenic prediction for the novel missense variants found in this study was performed with the Mitimpact 2 program.