Subproteomic profiling of sarcolemma from dystrophic mdx-4cv skeletal muscle

Sandra Murphy; Margit Zweyer; Michael Henry; Paula Meleady; Rustam R Mundegar; Dieter Swandulla; Kay Ohlendieck

doi:10.1016/j.dib.2018.02.020

Subproteomic profiling of sarcolemma from dystrophic mdx-4cv skeletal muscle

Data Brief. 2018 Feb 16:17:980-993. doi: 10.1016/j.dib.2018.02.020. eCollection 2018 Apr.

Authors

Sandra Murphy¹, Margit Zweyer², Michael Henry³, Paula Meleady³, Rustam R Mundegar², Dieter Swandulla², Kay Ohlendieck¹

Affiliations

¹ Department of Biology, Maynooth University, National University of Ireland, Maynooth, Co. Kildare, Ireland.
² Institute of Physiology II, University of Bonn, D-53115 Bonn, Germany.
³ National Institute for Cellular Biotechnology, Dublin City University, Dublin 9, Ireland.

Abstract

The proteomic data presented in this article provide supporting information to the related research article "Proteomic analysis of the sarcolemma-enriched fraction from dystrophic mdx-4cv skeletal muscle" (Murphy et al., 2018) [1]. In the associated research article, the sarcolemma from normal versus dystrophic skeletal muscle was analyzed by mass spectrometry-based proteomics. Sarcolemma vesicles were enriched by a lectin agglutination method and then analyzed by liquid chromatography tandem mass spectrometry. Here we provide additional datasets on proteins with decreased versus increased abundance in dystrophin-deficient muscle plasma membranes.