[The relationship between oxygen saturation and related respiratory events in patients with obstructive sleep apnea-hypopnea syndrome]

Abstract

Objective:To explore the relationship between variation of hemoglobin saturation and related respiratory events in patients with obstructive sleep apnea and hypopnea syndrome (OSAHS).Method:According to the SaO₂, the respiratory events were divided into two groups, followed or not followed the second events (SRE and N-SRE). Four features were extracted from SaO₂ and compared within groups under SRE versus N-SRE, and comparisons were also developed between moderate patients and severe patients.Result:ΔSaO₂, max, the duration and Dvmax was significantly higher in SRE than N-SRE (P< 0.01), while Nadir was significantly lower in SRE than N-SRE (P< 0.01). There was also significant difference in the blood oxygen index between moderate and severe patients. The change of SaO₂ is correlated with the ventilation restoration. The results also suggest that the severity of the patient's condition will affect the change of SaO₂ related indicators. Conclusion:This study provides information on the further study of ventilation restoration. Moreover, this study may provide a possible solution for the treatment of OSAHS.

Keywords: restoration of respiratory events; obstructive, sleep apnea and hypopnea syndrome; saturation.