[Analysis of the correlated factors and clinical features of 332 cases of fungal rhinosinusitis]

Abstract

Objective:To investigate the correlated factors and clinical features of fungal rhinosinusitis(FRS).Method:Retrospective analysis the clinical medical records of 332 cases of FRS(observation group) and 725 cases of chronic rhinosinusitis(control group) during 2007 to 2015 in our hospital including symptoms,signs,history,results of laboratory examinations and imaging findings.Then analysis and compare the differences between two groups of data.Result:The average age(50.25±13.42)years,the proportion of women(57.2%) and the time course of clinical symptoms<1 year(69.9%) ratio of observation group were significantly higher than that in control group, and all the differences were statistically significant(P<0.05).Clinical symptoms of observation group, such as haem nasal discharge,epistaxis,nose smelly, headaches,facial discomfort,were significantly higher than that in the control group, and percentages of nasal obstruction, pus snot and hyposphresia were significantly lower than that in the control group,all the differences had statistical significant(P<0.05).There was no statistically significant difference between two groups of nasal itching ratio(P>0.05).The rates of history of hypertension, diabetes, hyperthyroidism/hypothyroidism low hemoglobin in observation group, were notably higher than that in control group,and the rates of history of nasopharyngeal carcinoma radiotherapy and multiple history of nasal endoscopic surgery were notably lower than the control group,all the differences were statistical significant(P<0.05).There were no statistically significant difference(P>0.05) between the two groups smoking and drinking habits ratio.Single sinus disease,unilateral diseaseratio in observation group were obviously higher than that of control group,but the nasal septum deviation ratio significantly lower than the control group, the differences were statistically significant(P<0.05).Conclusion:There are many strong specificities of correlated factors and clinical features in FRS compared with CRS.It may help to make early intervention and clinical diagnosis depending on these specificities..

Keywords: clinical features; risk factors; sinusitis.