Middle Cranial Fossa Approach to Repair Tegmen Defects with Autologous or Alloplastic Graft

World Neurosurg. 2018 Oct:118:e10-e17. doi: 10.1016/j.wneu.2018.05.196. Epub 2018 Jun 2.

Abstract

Background: Temporal bone tegmen defects may be associated with cerebrospinal fluid (CSF) otorrhea. A variety of techniques have been used for repair. We report our experience with skull base reconstruction for tegmen defects using either autologous or alloplastic grafts.

Methods: A retrospective chart review was performed on patients with tegmen defects treated from 2007 to 2017 at the University Hospital in Columbia, Missouri, USA. Primary outcome measures were analyzed.

Results: Twenty-five patients were treated with a middle cranial fossa approach (median age 53, 88% females, median body mass index 34, median follow-up 9 months). Presenting symptoms included CSF leak (92%), hearing loss (44%), imbalance (12%), meningitis (12%), headache (4%), and tinnitus (4%). Most tegmen defects occurred spontaneously (84%) but cholesteatomas (4%), and trauma (12%) also were identified. Pre- and postoperative audiograms were available for 13 patients (52%); 7 (54%) showed objective improvement. Fourteen patients were repaired with autologous bone graft (56%), 7 with alloplastic grafts (28%), and 4 with temporalis fascia only (16%). All patients had resolution of CSF leak. Two patients (8%) suffered wound infections and 3 (12%) had facial and/or petrosal nerve complications. Use of alloplastic graft significantly shortened operative time (allopathic mean 180 minutes vs. autologous mean 208 minutes; P = 0.03).

Conclusions: CSF otorrhea due to tegmen defects can be repaired via a middle fossa craniotomy using either an autologous or alloplastic graft with equivalent outcomes and efficacy, although alloplastic graft helps reduce operating time.

Keywords: CSF otorrhea; Encephalocele; Hearing loss; MEDPOR; Mastoidectomy; Middle fossa craniotomy; Tegmen defect.

MeSH terms

  • Adult
  • Aged
  • Bone Transplantation / methods*
  • Cranial Fossa, Middle / abnormalities
  • Cranial Fossa, Middle / diagnostic imaging*
  • Cranial Fossa, Middle / surgery*
  • Craniotomy / methods*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Retrospective Studies
  • Temporal Bone / abnormalities
  • Temporal Bone / diagnostic imaging
  • Temporal Bone / surgery
  • Transplantation, Autologous / methods