Chemical constituents of Ligularia hookeri (Asteraceae) collected in Yunnan and Sichuan Provinces in China were examined for the first time. Seven furanoeremophilanes, five of which were new, as well as known bisabolane- and eudesmane-type sesquiterpenoids, were isolated. Spectroscopic evidence indicates that the previously reported 3β-(2'-methylpropenoyloxy)furanoeremophilan-15,6β-olide should be revised to 3β-(2'-methylpropenoyloxy)furanoeremophilan-15,6α-olide.
Keywords: Asteraceae; Ligularia hookeri; eremophilane; internal transcribed spacer; sesquiterpene; structure elucidation.