Near-Infrared Spectroscopy Imaging for Assessing Skin and Wound Oxygen Perfusion

Clin Podiatr Med Surg. 2018 Jul;35(3):343-355. doi: 10.1016/j.cpm.2018.02.005. Epub 2018 May 3.

Abstract

Near infrared spectroscopy (NIRS) is a technique whereby light is transmitted to the skin or the surface of a wound. Light is selectively absorbed or reflected in order to calculate the percentage of oxygenated and deoxygenated hemoglobin. By calculating this ratio, the level of tissue oxygen perfusion can be assessed. This article describes an NIRS imaging device and demonstrates its use as a clinical tool to predict future viability of skin flaps, potential for wound healing, and progress of closure following application of a biologic wound product. Several cases are examined.

Keywords: Healing rate; NIRS; Near-infrared spectroscopy; Oxygenated hemoglobin; Tissue oxygen perfusion; Tissue oxygenation; Wound perfusion.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Aged
  • Female
  • Foot Injuries / diagnosis*
  • Foot Injuries / surgery
  • Foot Ulcer / diagnosis*
  • Foot Ulcer / surgery
  • Hemoglobins / metabolism
  • Humans
  • Male
  • Oxygen / metabolism*
  • Spectroscopy, Near-Infrared*
  • Surgical Flaps / blood supply
  • Surgical Flaps / physiology*
  • Wound Healing / physiology*

Substances

  • Hemoglobins
  • deoxyhemoglobin
  • Oxygen