Nuclear factor (erythroid-derived 2)-like-2 pathway modulates substance P-induced human mast cell activation and degranulation in the hair follicle

Affiliations

• ¹ Centre for Dermatology Research, University of Manchester, MAHSC and NIHR Manchester Biomedical Research Centre, Manchester, United Kingdom.
• ² Centre for Dermatology Research, University of Manchester, MAHSC and NIHR Manchester Biomedical Research Centre, Manchester, United Kingdom; Manchester Collaborative Centre for Inflammation Research (MCCIR), University of Manchester, Manchester, United Kingdom.
• ³ Farjo Medical Centre, Manchester, United Kingdom.
• ⁴ Unilever R&D Colworth, Colworth Science Park, Bedfordshire, United Kingdom.
• ⁵ Centre for Dermatology Research, University of Manchester, MAHSC and NIHR Manchester Biomedical Research Centre, Manchester, United Kingdom; Department of Biological Sciences, School of Applied Sciences, University of Huddersfield, Huddersfield, United Kingdom.
• ⁶ Centre for Dermatology Research, University of Manchester, MAHSC and NIHR Manchester Biomedical Research Centre, Manchester, United Kingdom; Department of Dermatology, University of Miami, Miller School of Medicine, Miami, Fla. Electronic address: ralf.paus@manchester.ac.uk.