Investigation of iron deficiency anaemia

Clin Med (Lond). 2018 Jun;18(3):242-244. doi: 10.7861/clinmedicine.18-3-242.

Abstract

Iron deficiency anaemia (IDA) is an important, common clinical condition and 8-15% of these patients will be diagnosed with a gastrointestinal cancer. IDA is defined as haemoglobin below the lower limit of normal, in the presence of characteristic iron studies. This article will discuss the causes and clinical diagnosis of iron deficiency, including interpretation of common laboratory tests that differentiate this from other causes of anaemia. We suggest an initial approach for investigating the cause of iron deficiency in these patients and also consider the subsequent treatment and indications for further investigation.

Keywords: anaemia; haemogloblin; iron deficiency.

Publication types

  • Review

MeSH terms

  • Age Factors
  • Anemia, Iron-Deficiency / blood
  • Anemia, Iron-Deficiency / diagnosis*
  • Anemia, Iron-Deficiency / etiology
  • Anemia, Iron-Deficiency / metabolism
  • Celiac Disease / complications
  • Celiac Disease / diagnosis*
  • Colonoscopy
  • Erythrocyte Indices
  • Ferritins / metabolism
  • Gastrointestinal Neoplasms / complications
  • Gastrointestinal Neoplasms / diagnosis*
  • Gastroscopy
  • Hemoglobins / metabolism
  • Humans
  • Iron / metabolism
  • Receptors, Transferrin

Substances

  • Hemoglobins
  • Receptors, Transferrin
  • Ferritins
  • Iron