Detection of virulence and β-lactamase encoding genes in Enterobacter aerogenes and Enterobacter cloacae clinical isolates from Brazil

Braz J Microbiol. 2018 Nov;49 Suppl 1(Suppl 1):224-228. doi: 10.1016/j.bjm.2018.04.009. Epub 2018 May 21.

Abstract

Enterobacter cloacae and E. aerogenes have been increasingly reported as important opportunistic pathogens. In this study, a high prevalence of multi-drug resistant isolates from Brazil, harboring several β-lactamase encoding genes was found. Several virulence genes were observed in E. aerogenes, contrasting with the E. cloacae isolates which presented none.

Keywords: Enterobacter aerogenes; Enterobacter cloacae; Resistance; Virulence.

MeSH terms

  • Adult
  • Aged
  • Anti-Bacterial Agents / pharmacology
  • Bacterial Proteins / genetics
  • Bacterial Proteins / metabolism*
  • Brazil
  • Enterobacter aerogenes / classification
  • Enterobacter aerogenes / enzymology
  • Enterobacter aerogenes / genetics
  • Enterobacter aerogenes / isolation & purification*
  • Enterobacter cloacae / classification
  • Enterobacter cloacae / enzymology
  • Enterobacter cloacae / genetics
  • Enterobacter cloacae / isolation & purification*
  • Enterobacteriaceae Infections / microbiology*
  • Female
  • Humans
  • Male
  • Microbial Sensitivity Tests
  • Middle Aged
  • Phylogeny
  • Virulence
  • Virulence Factors / genetics
  • Virulence Factors / metabolism*
  • beta-Lactamases / genetics
  • beta-Lactamases / metabolism*

Substances

  • Anti-Bacterial Agents
  • Bacterial Proteins
  • Virulence Factors
  • beta-Lactamases