Gastro-intestinal surgery and fertility

J Visc Surg. 2018 Jun:155 Suppl 1:S49-S55. doi: 10.1016/j.jviscsurg.2018.04.006. Epub 2018 May 30.

Abstract

In France, 10 to 15% of couples in the overall population have a fertility problem. Preservation of sexual and reproductive function should be a major concern for all patients capable of procreation who undergo treatment for gastro-intestinal disease. The gastro-intestinal diseases most often responsible for fertility disorders include chronic inflammatory diseases, intestinal cancer and hereditary diseases, such as the Lynch syndrome and familial adenomatous polyposis. Obesity is responsible for a 20% loss of fertility but the effects of bariatric surgery on fertility are controversial. Nonetheless, in the light of progress in surgical techniques and better knowledge of gastro-intestinal disease the negative impact of surgery on fertility warrants attention. Effectively, fertility can be preserved after certain major gastro-intestinal operations such as cytoreductive surgery with intraperitoneal chemotherapy, total coloprotectomy with ileo-anal anastomosis and rectosigmoid resection, as long as the patient's age permits and resection of the reproductive organs is not necessary.

Keywords: Chronic digestive diseases; Digestive surgery; Fertility.

Publication types

  • Review

MeSH terms

  • Digestive System Surgical Procedures / adverse effects
  • Digestive System Surgical Procedures / methods*
  • Fertility Preservation / methods*
  • Humans
  • Infertility / etiology
  • Infertility / prevention & control*
  • Postoperative Complications / prevention & control*