Personalized Dietary Management of Overweight and Obesity Based on Measures of Insulin and Glucose

Annu Rev Nutr. 2018 Aug 21:38:245-272. doi: 10.1146/annurev-nutr-082117-051606. Epub 2018 Jun 1.

Abstract

During the past several decades, numerous trials have compared various diets for the management of overweight and obesity, assuming that a single dietary strategy would be appropriate for all individuals. These studies have failed to provide strong evidence for the efficacy of any particular diet, and it is likely that different people will have different levels of success on different diets. We identified studies investigating pretreatment glycemia or insulinemia status, or both, of the individual as prognostic markers of weight loss during periods in which the composition of a participant's diet was known. Overall, research suggests that providing specific diets for weight management based on pretreatment glycemia and insulinemia statuses holds great promise for advancing personalized nutrition.

Keywords: glucose; insulin; overweight; personalized nutrition.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Blood Glucose*
  • Humans
  • Insulin / blood*
  • Overweight / blood*
  • Overweight / diet therapy*
  • Overweight / metabolism
  • Precision Medicine*
  • Weight Loss*

Substances

  • Blood Glucose
  • Insulin