Atypical sarcoidosis-associated uveitis: diagnostic challenges

BMJ Case Rep. 2018 May 30:2018:bcr2018225137. doi: 10.1136/bcr-2018-225137.

Abstract

Sarcoidosis is a multisystem disease of unknown aetiology with pulmonary involvement in most patients. Uveitis is common and often characteristic. We report a case of ocular sarcoidosis with grossly atypical contiguous optic neuropathy and choroiditis and describe the diagnostic challenges in this highly unusual presentation. High-dose systemic corticosteroid and immunosuppressive treatment was required for sustained control of intraocular inflammation.

Keywords: eye; retina.

Publication types

  • Case Reports

MeSH terms

  • Adrenal Cortex Hormones / administration & dosage
  • Azathioprine / administration & dosage
  • Choroiditis / diagnosis
  • Choroiditis / drug therapy
  • Diagnosis, Differential
  • Drug Administration Schedule
  • Drug Therapy, Combination
  • Eye Diseases / diagnosis*
  • Eye Diseases / drug therapy
  • Female
  • Humans
  • Immunosuppressive Agents / administration & dosage
  • Methylprednisolone / administration & dosage
  • Middle Aged
  • Optic Nerve Diseases / diagnosis
  • Optic Nerve Diseases / drug therapy
  • Positron Emission Tomography Computed Tomography
  • Prednisolone / administration & dosage
  • Sarcoidosis / diagnosis*
  • Sarcoidosis / drug therapy
  • Tomography, Optical Coherence
  • Uveitis / diagnosis
  • Uveitis / drug therapy

Substances

  • Adrenal Cortex Hormones
  • Immunosuppressive Agents
  • Prednisolone
  • Azathioprine
  • Methylprednisolone