Pharmacologic therapy with flecainide for asymptomatic Wolff-Parkinson-White syndrome in an infant with severe left ventricular dyssynchrony

Cardiol Young. 2018 Jul;28(7):970-973. doi: 10.1017/S1047951118000252.

Abstract

Some asymptomatic patients with Wolff-Parkinson-White syndrome have severe left ventricular dyssynchrony and dysfunction. We describe a patient who was given a diagnosis of Wolff-Parkinson-White syndrome in infancy and had a complete response to pharmacologic therapy with flecainide. Our findings suggest that flecainide is a suitable resynchronisation therapy for such infants.

Keywords: Wolff–Parkinson–White syndrome; flecainide; left ventricular dyssynchrony; resynchronisation therapy.

Publication types

  • Case Reports

MeSH terms

  • Anti-Arrhythmia Agents / therapeutic use*
  • Echocardiography
  • Electrocardiography, Ambulatory
  • Flecainide / therapeutic use*
  • Heart Ventricles / physiopathology
  • Humans
  • Infant
  • Male
  • Ventricular Dysfunction, Left / complications*
  • Wolff-Parkinson-White Syndrome / diagnostic imaging*
  • Wolff-Parkinson-White Syndrome / drug therapy*

Substances

  • Anti-Arrhythmia Agents
  • Flecainide